Shingles (Herpes Zoster) Vaccination | CDC Vaccines & Preventable Diseases Home Vaccines by Disease Shingles (Herpes Zoster) Vaccination Shingles is a painful rash that usually develops on one side of the body, often the face or torso. You can review and change the way we collect information below. Both Shingrix and Zostavax shingles vaccines have been shown to be safe and well tolerated. ", ProCon.org. Vaccination is a safe and effective way to protect you from serious disease caused by shingles. Many people have redness and swelling on their arm spanning several inches where they got the shot. Before you administer Shingrix, CDC recommends counseling your patients about the common reactions to the vaccine. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. CDC uses 3 systems to monitor vaccine safety: English D. Willis, Meredith Woodward, Elizabeth Brown, Zoran Popmihajlov, Patricia Saddier, Paula W. Annunziato, Neal A. Halsey, Anne A. Gershon, Herpes zoster vaccine live: A 10year review of post-marketing safety experience. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. The most common complication of shingles is long-term nerve pain called postherpetic neuralgia (PHN). Shingles is more common in older adults, people who have medical conditions that weaken the immune system, and people who take medications that suppress their immune systems. Shingles is a painful rash that usually develops on one side of the body, often the face or torso. In rare cases, people who got vaccinated with Zostavax experienced a blister-like rash; some were found to have been caused by the vaccine. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. 33. Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia(PHN), the most common complication from shingles. The two doses should be separated by two to six months. 8. They help us to know which pages are the most and least popular and see how visitors move around the site. Cabbage moth and fall armyworm cells are used to grow viruses for vaccines. Know the benefits and side effects of Shingrix so youre prepared to talk with your patients before administering the vaccine. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Most side effects are mild to moderate lasting 2-3 daysand could affect normal daily activities. 2012 Apr;54(7):922-8. Rarely, shingles can lead to complications such as pneumonia, hearing problems, blindness, brain inflammation (encephalitis), or death. Saccharomyces cerevisiae cells, aluminum hydroxide, listyeast protein. Strongly recommend your patients get the second dose of the vaccine even if they experience these side effects to ensure maximum protection from shingles. Vermeulen JN, Lange JM, Tyring SK, Peters PH, Nunez M, et al. You may get the Shingrix vaccine even if you've already had shingles. If such reactions occur, call 9-1-1 and get the person to the nearest hospital. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Healthcare providers and vaccine manufacturers are required by law to report certain adverse events following vaccination to VAERS; patients and caregivers can also submit reports. Cohen J. anhydrous lactose, microcrystalline cellulose, polacrilin potassium, magnesium stearate, live adenovirus [Type 4 or Type 7, dried substance includes monosodium glutamate, sucrose, D-mannose, D-fructose, dextrose, human serum albumin, potassium phosphate, and plasdone C], microcrystalline cellulose, magnesium stearate, and anhydrous lactose, cellulose acetate phthalate, alcohol, acetone, castor oil; Type 7 tablet also contains FD&C Yellow #6 aluminum lake dye. You should not give Shingrix to a patient who has ever had a severe allergic reaction, such as anaphylaxis, to a component of this vaccine, or after a dose of Shingrix. See, A 2012 study found a small risk for allergic reactions 1 to 7 days after Zostavax. Winstar Institute 38 is the human diploid lung fibroblasts derived from the lung tissues of a female fetus aborted because the family felt they had too many children in 1964 in the United States. glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron ammonium citrate Vaccine Ingredients: (in addition to the virus strain (s) being vaccinated against) lactose, sterile water BCG Live Manufacturer: Organon Teknika Corp. Tice BCG Package Insert (Feb. 2009) Growth Mediums and Process Ingredients: Many people also felt tired or experienced muscle pain, a headache, shivering, fever, stomach pain, or nausea. World Health Organization, Production and Control of Tetanus Vaccine: A Training Curriculum, Module III: Principles of Tetanus Vaccine Production, who.int, Sep. 3, 1999, ProCon/Encyclopaedia Britannica, Inc. Baxter R, Tran TN, Hansen J, Emery M, Fireman B, et al. Some vaccines, like influenza (flu) vaccines, are modified frequently and you may wish to consult your doctors office or pharmacy for the most current information. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Martin M. Dworkin, Stanley Falkow, Karl-Heinz Schleifer, and Erko Stackebrandt, 2006. Also, you are more likely to have severe, long-term pain if you get shingles when you are older. Gelatin is used to protect viruses in vaccines from freeze-drying or heat and to stabilize vaccines so they stay stable. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Centers for Disease Control and Prevention. However, there are no data or theoretical concerns to indicate that Shingrix would be less safe or less effective when given at an interval shorter than 5 years following Zostavax. Tseng HF, Liu A, Sy L, Marcy SM, Fireman B, et al. A sore arm with mild or moderate pain is very common after recombinant shingles vaccine. Your reaction to each dose may be different; just because you have a reaction to the first dose does not mean that you will have a reaction to the second. Reporting is encouraged for any clinically significant adverse event even if it is uncertain whether the vaccine caused the event. Among immunocompetent adults 50 years and older, the efficacy of two doses of Shingrix for the prevention of herpes zoster (shingles) was high among all age groups. PHN occurs in the areas where the shingles rash was and can last for months or years after the rash goes away. You will be subject to the destination website's privacy policy when you follow the link. Saving Lives, Protecting People, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. Shingrix (recombinant zoster vaccine) is a suspension for injection supplied as a single-dose vial of lyophilized gE antigen component to be reconstituted with the accompanying vial of AS01B adjuvant suspension component. Severe allergic reactions following vaccination are rare, but can be life threatening. The Centers for Disease Control and Prevention (CDC) recommends that older and immunocompromised adults get two doses of Shingrix (the recombinant zoster vaccine, or RZV) to prevent shingles and related complications. aluminum hydroxide, sodium chloride, phosphate buffers [disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate], Hepatitis B Vaccine (Recombinant), Adjuvanted, Manufacturer: Dynavax Technologies Corporation, Hansenula polymorpha yeast, fermentation media [vitamins, mineral salts], CpG 1018 adjuvant [22-mer phosphorothioate linked oligodeoxynucleotide, phosphate buffered saline (sodium chloride, sodium phosphate, dibasic dodecahydrate, monobasic dihydrate, polysorbate 80)], yeast protein, yeast DNA, deoxycholate, CpG 1018, Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant, Saccharomyces cerevisiae, fermentation media [vitamins, amino acids, mineral salts, carbohydrates], amorphous aluminum hydroxyphosphate sulfate, amorphous aluminum hydroxyphosphate sulfate adjuvant, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus 9-valent Vaccine, Recombinant, amorphous aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water, Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant, serum-free culture media [lipids, vitamins, amino acids, mineral salts], hydroxide salt, AS04 [3-O-desacyl-4-monophosphoryl lipid A (MPL), hydroxide salt, sodium chloride, sodium dihydrogen phosphate dihydrate, water, 3-O-desacyl-4-monophosphoryl lipid A (MPL), aluminum hydroxide, sodium chloride, sodium dihydrogen phosphate dihydrate, insect cell and viral protein, bacterial cell protein, 19. Hep A & Hep B Vaccine(hepatitis A & hepatitis B), Hepatitis A Inactivated and Hepatitis B (Recombinant) Vaccine, MRC-5 human diploid cells, formalin, Saccharomyces cerevisiae yeast cells, aluminum salts, listaluminum phosphate, aluminum hydroxide, amino acids, sodium chloride, phosphate buffer, polysorbate 20, water, formalin, MRC-5 cellular proteins, neomycin sulfate, yeast protein, yeast cells, fermentation medium [extract of yeast, soy peptone, dextrose, amino acids, mineral salts], phosphate buffer, formaldehyde, potassium aluminum sulfate, amorphous aluminum hydroxyphosphate sulfate. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. in adults aged 18 years and older who are or will be at increased risk of HZ due to immunodeficiency or immunosuppression caused by known disease or therapy. Common Ingredients: beef extract, acid hydrolysate of casein, starch, agar, Common Ingredients: glucose, sodium chloride, sodium phosphate dibasic, monopotassium, phosphate, magnesium sulfate hydrate, ferrous sulfate heptaphydrate, cystine hydrochloride, tyrosine hydrochloride, urasil hydrochloride, Ca-pantothenate in ethanol, thiamine in ethanol, pyridoxin-hydrochloride in ethanol, riboflavin in ethanol, biotin in ethanol, sodium hydroxide, beef heart infusion (de-fatted beef heart and distilled water), casein solution. loss of bladder or bowel control. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. More information on Emergency Use Authorization (EUA) and the COVID-19 vaccines may be found on the FDA site. Cochrane Database Syst Rev. CDC twenty four seven. That vaccine is offered outside of the United States. Symptoms usually go away on their own in 2 to 3 days. Seefried, M.J. Walton, and H.G. It is caused by the varicella-zoster virus (VZV), the same virus that causes chickenpox. About 1 out of 6 people had symptoms severe enough to prevent them from doing regular activities. Tiredness, muscle pain, headache, shivering, fever, stomach pain, and nausea are common after recombinant shingles vaccine. Remind your patients that the pain from shingles can last a lifetime, and these side effects should only last 2 to 3 days. Most often these components are whole viruses or bacteria, parts of the viruses or bacteria, or products made by bacteria, called toxins. Also called Tween 80, Alkest 80, or Canarcel 80 (brand names), Polysorbate 80 is used as an excipient (something to basically thicken a vaccine for proper dosing) and an emulsifier (something to bond the ingredients). DTap-IPV (diphtheria, tetanus, pertussis, & polio), 11. Shingles (also called herpes zoster, or just zoster) is a painful skin rash, usually with blisters. She . 90.5% in a post hoc efficacy analysis of adult patients with immune-mediated diseases who were not taking immunosuppressive medication. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Common Ingredients: Cells from normal female adult Cocker Spaniel (harvested in 1958 by SH Madin and NB Darby), EMEM(EBSS) (Eagle's Minimum Essential Medium with Earle's Balanced Salt Solution), glutamine, non essential amino acids, foetal bovine serum. NEJM. Common questions about vaccine ingredients Some people describe the pain as an intense burning sensation. 2017 Dec 19:35(52):7231-7239. aluminum phosphate, isotonic sodium chloride solution, free formaldehyde. If they have a reaction to the first dose of Shingrix, it does not necessarily mean they will have a reaction to the second dose. CDC recommends Shingrix as the preferred vaccine, over Zostavax, to prevent shingles and the complications from the disease. Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Shingrix is also recommended for adults 19 years and older who have weakened immune systems because of disease or therapy. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Shingrix is a new adjuvanted, non-live recombinant shingles vaccine. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. ProCon.org is the institutional or organization author for all ProCon.org pages. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. The vaccine is also recommended for people who have already gotten another type of shingles vaccine, the live shingles vaccine. CDC recommends two doses of recombinant zoster vaccine (RZV, Shingrix) to prevent shingles and related complications in adults 50 years and older. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. We take your privacy seriously. It does not have a live virus. Shingles Vaccine Ingredients Shingrix is a recombinant vaccine. among people with autoimmune conditions, people with weakened immune systems, and people over 80 years old. . ], [Editors Note: The MLA citation style requires double spacing within entries. The Pfizer COVID-19 vaccine has been approved for non-emergency use and is included below. 2010 Jun 7;28(25):4204-9. You should tell patients to expect such reactions as pain, swelling, and redness . Vero cells were derived from the kidney of a normal, adult African Green monkey in 1962 by Y. Yasumura and Y. Kawakita. Many Vaccine Information Statements are available in espaol and other languages. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. They help us to know which pages are the most and least popular and see how visitors move around the site. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Some vaccines against COVID-19 also use nucleic acids. Vaccine. Who should get vaccinated against shingles Advisory Committee on Immunization Practices (ACIP) Centers for Disease Control and Prevention (CDC). The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Common Ingredients: Medical Research Council 5, human diploid cells (cells containing two sets of chromosomes) derived from the normal lung tissues of a 14-week-old male fetus aborted for "psychiatric reasons" in 1966 in the United Kingdom, Eagle's Basal Medium in Earle's balanced salt solution with bovine serum. Tell your patients to contact their health insurance providers ahead of time to see if they will cover the vaccine. Safety, tolerability, and immunogenicity of zoster vaccine in subjects with a history of herpes zoster. All rights reserved. Healy, S. Teleki, A.V. 2011 Nov;7(11):1130-6. DTaP-IPV-Hib (diphtheria, tetanus, pertussis, polio, & haemophilus influenzae type B), 16. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Thank you for taking the time to confirm your preferences. The efficacy of two doses of Shingrix for the prevention of postherpetic neuralgia (PHN) was high: 91.2% in adults aged 50 years and older, and 88.8% in adults aged 70 years and older. Vaccines for preventing herpes zoster in older adults. Some people who have or will have a weakened immune system can get the second dose 1 to 2 months after the first dose. Protection stays above 85% for at least the first four years after you get vaccinated. Rarely, shingles can lead to complications such as pneumonia, hearing problems, blindness, brain inflammation (encephalitis), or death. Shingrix is administered in two doses, usually two to six months apart. Shingrix, a vaccine for the prevention of shingles in adults 50 years of age and older, includes AS01B. CDC twenty four seven. 2014 Aug 22; 63(33):729-731. ProCon.org. 2012 Oct 17;10:CD008858. Your risk of getting shingles and PHN increases as you get older. ], sodium chloride, lipids ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2-(polyethylene glycol 2000)-N,N-ditetradecylacetamide, 1,2-distearoyl-sn-glycero-3-phosphocholine, cholesterol), potassium chloride, monobasic potassium phosphate, dibasic sodium phosphate dihydrate, sucrose, Vero cells (African Green Monkey kidney), stabilizer solution, sodium chloride, essential amino acids (including L-phenylalanine), non-essential amino acids, L-arginine hydrochloride, sucrose, D-trehalose dihydrate, D-sorbitol, trometamol, urea, aluminum phosphate, isotonic sodium chloride solution, formalin, tryptic digest of casein, cystine, maltose, uracil, inorganic salts, vitamins, 8. The risk of PHN increases with age. Hib Vaccine(haemophilus influenzae type B), Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate), amorphous aluminum hydroxyphosphate sulfate (previously referred to as aluminum hydroxide), sodium chloride, Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate), semi-synthetic medium, ammonium sulfate, Mueller and Miller medium, milk-derived raw materials (casein derivatives), saline diluent, purified capsular polysaccharide, synthetic medium, semi-synthetic medium, formaldehyde, lactose, sterile saline solution, purified capsular polysaccharide, lactose, formaldehyde, aluminum hydroxide, amino acid supplement, phosphate-buffered saline solution, polysorbate 20, MRC-5 cellular proteins, formalin, neomycin sulfate, MRC-5 diploid fibroblasts, amorphous aluminum hydroxyphosphate sulfate, nonviral protein, DNA, bovine albumin, formaldehyde, neomycin, amorphous aluminum hydroxyphosphate sulfate, sodium borate, sodium chloride, 16. Both vials of Shingrix must be refrigerated at a temperature of 36-46 F. Do not use if exposed to temperatures below 36 F. Prepare Shingrix by reconstituting the antigen component with the adjuvant suspension component. Vaccine. Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. DTaP Vaccine(diphtheria, tetanus, & pertussis), Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Manufacturer: GlaxoSmithKline Biologicals, Fenton medium (containing bovine extract), Latham medium, Stainer-Scholte liquid medium, glutaraldehyde, formaldehyde, aluminum hydroxide. All information these cookies collect is aggregated and therefore anonymous. You can submit a report of your side effects to the Vaccine Adverse Event Reporting System through the website (. . For some people, the pain can last for months or even years after the rash goes away. Shingrix is recommended by the Centers for Disease Control and Prevention (CDC) for adults age 50 and older for the prevention of shingles and related complications, whether they've already had shingles or not. problems with balance or eye movement; or. They help us to know which pages are the most and least popular and see how visitors move around the site. 2021), Madin Darby Canine Kidney (MDCK) cells, culture medium, -propiolactone, cetyltrimethylammonium bromide, phosphate buffered saline, MDCK cell protein, protein other than HA, MDCK cell DNA, polysorbate 80, cetyltrimethylammonium bromide, propiolactone, thimerosal, Influenza Virus Vaccine (Trivalent, Types A and B), Afluria Southern Hemisphere Package Insert (2021), Afluria: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta375 propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution, Afluria Southern Hemisphere: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta-propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution, Afluria: sodium chloride, monobasic sodium, phosphate, dibasic sodium phosphate, monobasic potassium phosphate, potassium chloride, calcium chloride, sodium taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, beta-propiolactone, hydrocortisone, Afluria Southern Hemisphere: thimerosal, sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, monobasic potassium phosphate, potassium chloride, calcium chloride, sodium taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, beta-propiolactone, hydrocortisone, phosphate-buffered saline solution, thimerosal, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Influenza Vaccine, Live, Intranasal (Trivalent, Types A and B), [Editors Note: This vaccine was approved on July 9, 2020, and, as of Nov. 1, 2021, the FDA had not uploaded the package insert. CDC recommends the shingles vaccine (Shingrix) for adults 50 and older, Give Shingrix to immunocompetent adults 50 years and older, including those who. procon@eb.com, 2022 Encyclopaedia Britannica, Inc. Get CDCs official recommended immunization schedules for children, adolescents, and adults. Stainer-Scholte medium, casamino acids, dimethyl-beta-cyclodextrin, glutaraldehyde, formaldehyde, aluminum phosphate, Muellers growth medium, ammonium sulfate, Mueller-Miller casamino acid medium (without beef heart infusion), 2-phenoxyethanol, water, filamentous hemagglutinin (FHA), pertactin (PRN), fimbriae types 2 and 3 (FIM), aluminum phosphate, formaldehyde, glutaraldehyde, 2-phenoxyethanol, 9. Other effects include: Many people who get the vaccine have muscle aches, headaches, or feel tired. Most side effects are mild to moderate, and last 1-3 days. 2016:375(11), 1019-32. Manufacturer: Emergent Travel Health, Inc. Vaxchora Frozen Package Insert (June 2016)Vachora Package Insert (Dec. 2020), frozen: casamino acids, yeast extract, mineral salts, anti-foaming agent, ascorbic acid, Hy-Case SF, sodium chloride, sucrose, dried lactose, other: casamino acids, yeast extract, mineral salts, anti-foaming agent, ascorbic acid, Hy-Case SF, sucrose, anhydrous lactose, frozen: sodium bicarbonate, sodium carbonate, ascorbic acid, dried lactose, sucrose, sodium chloride, Hy-Case SF, other: sodium bicarbonate, sodium carbonate, ascorbic acid, anhydrous lactose, sucrose, Hy-Case SF, anhydrous lactose, Manufacturer: BioNTech Manufacturing GmbH, [Editors Note: This vaccine is commonly known as the Pfizer coronavirus vaccine. Formaldehyde is used in vaccines to inactivate the virus so the person being inoculated does not contract the disease. Since the risk of herpes zoster increases with age, providers should weigh a patients risk of herpes zoster with the age-specific protection expected from Zostavax to determine when to vaccinate with Shingrix. Zostavax is made from the whole but . Murray AV, Reisinger KS, Kerzner B, Stek JE, Sausser TA, et al. Morrison VA, Oxman MN, Levin MJ, Schmader KE, Betts RF, et al. Severe allergic reactions to Shingrix are very rare. To receive email updates about this page, enter your email address: We take your privacy seriously. Cookies used to make website functionality more relevant to you. More information about contraindications and precautions. Centers for Disease Control and Prevention. Shingrix (recombinant zoster vaccine) is a suspension for injection supplied as a single-dose vial of lyophilized gE antigen component to be reconstituted with the accompanying vial of AS01 B adjuvant suspension component. Side effects are more common in younger people. There is no live virus in recombinant shingles vaccine. Here are the proper bibliographic citations for this page according to four style manuals (in alphabetical order): [Editor's Note: The APA citation style requires double spacing within entries. Vaccine Information Statement Manufacturer: Wyeth Pharmaceuticals, Inc. E. coli, fermentation growth media, polysorbate 80 (PS80), polysorbate 80, Al+ as AlPO4, histidine buffered saline, Meningococcal Polysaccharide Vaccine, Groups A, C, Y and W-135 Combined, Menomune-A/C/Y/W-135 Package Insert (Mar. Accessed February 21, 2023. https://vaccines.procon.org/vaccine-ingredients-and-manufacturer-information/, Born Gay? Zostavax [PDF - 13 Pages] The FDA licensed Zostavax in 2006 to prevent shingles. Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. Your health care provider will usually file this report, or you can do it yourself. Manufacturer: Emergent Product Development Gaithersburg, Inc. HEPES, human serum albumin, sodium chloride, mannitol, neomycin, polymyxin B, diluent [glycerin, phenol, water], TDVAX (NDC 14362-0111) Package Insert (Sep. 2018), TDVAX (NDC 13533-131) Package Insert (Sep. 2018), TDVAX (NDC 14362-0111): modified Muellers media, formaldehyde, ammonium sulfate, aluminum phosphate, TDVAX (NDC 13533-131): modified Muellers media, formaldehyde, ammonium sulfate, aluminum phosphate, TDVAX (NDC 14362-0111): aluminum, formaldehyde, thimerosal, TDVAX (NDC 13533-131): aluminum, formaldehyde, thimerosal, Tetanus & Diphtheria Toxoids Adsorbed for Adult Use, modified Mueller-Miller casamino acid medium without beef heart infusion, formaldehyde, ammonium sulfate, modified Muellers growth medium, aluminum phosphate, aluminum phosphate, formaldehyde, sodium chloride, water, formalin, culture medium [casein, cystine, maltose, uracil, inorganic salts, vitamins]. These would start a few minutes to a few hours after the vaccination. The CDC recommends that everyone aged 50 or older get Shingrix. "Vaccine Ingredients and Manufacturer Information." DTaP (diphtheria, tetanus, & pertussis), 9. These can include cool. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Schmader KE, Levin MJ, Gnann JW Jr, McNeil SA, Vesikari T, et al. ], ProCon.org, "Vaccine Ingredients and Manufacturer Information,", ProCon.org, "Vaccine Ingredients and Manufacturer Information. Thank you for taking the time to confirm your preferences. Package insert for Shingrix, U.S. Food and Drug Administrationpdf iconexternal icon, Shingles Vaccine Information Statement (Shingrix), National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. Saving Lives, Protecting People, Protect your patients with the shingles vaccine, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services, received Zostavax at least 8 weeks prior, have health conditions, such as chronic renal failure, diabetes mellitus, rheumatoid arthritis, or chronic pulmonary disease, are receiving other vaccines, such as influenza and pneumococcal vaccines, at the same visit, are taking low-dose immunosuppressive therapy. Thimerosal is an organomercury compound used as a preservative. Your health care provider can give you more information. 2-Phenoxyethanol is a glycol ether used as a preservative in vaccines. You need to come back in 2 to 6 months for your second dose. You should get the shingles vaccine even if you: Safety of zoster vaccine in adults from a large managed-care cohort: A Vaccine Safety Datalink study. Antigens can be considered the active ingredients in vaccines because they are the parts of the vaccine to which an immune response is generated. 2021), sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, and polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Influenza Vaccine,Live, Intranasal (Quadrivalent, Types A and Types B), FluMist Quadrivalent Package Insert (Aug. 2021), specific pathogen-free (SPF) eggs, stabilizing buffer, monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA), Influenza Virus Vaccine (Quadrivalent, Types A and Types B), Manufacturer: Glaxosmithkline Biologicals, Fluarix Quadrivalent Package Insert (2021), octoxynol-10 (TRITON X-100), tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, Fluzone High-Dose Quadrivalent Package Insert (July 2021), Fluzone Quadrivalent Package Insert (2021), Fluzone Intradermal Quadrivalent Package Insert (May 10, 2016), Fluzone Quadrivalent Southern Hemisphere Package Insert (2021), Fluzone High-Dose Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution , octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent Southern Hemisphere: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Quadrivalent: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Intradermal Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Quadrivalent Southern Hemisphere: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Flulaval Quadrivalent Package Insert (2021), phosphate-buffered saline solution, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed, Vero cells, protamine sulfate, sucrose density gradient, formaldehyde, aluminum hydroxide, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein, protamine sulfate, 23. `` vaccine ingredients some people describe the pain from shingles Vesikari T, et al of to... Providers ahead of time to confirm your preferences SK, Peters PH, M! That everyone aged 50 or older get Shingrix the MLA citation style requires spacing! A report of your side effects are mild to moderate lasting 2-3 could. 1 to 2 months after the first dose common after recombinant shingles vaccine, over Zostavax, prevent. Fever, stomach pain, redness, and nausea are common after recombinant shingles vaccine Use!, Levin MJ, Gnann JW Jr, McNeil SA, Vesikari T, al. Them from doing regular activities Dec 19:35 ( 52 ):7231-7239. aluminum phosphate, isotonic sodium chloride solution free. Schmader KE, Betts RF, et al ( diphtheria, tetanus, haemophilus... `` vaccine ingredients and Manufacturer information, adult African Green monkey in 1962 by Yasumura! L, Marcy SM, Fireman B, et al of shingles vaccine Y. Yasumura and Kawakita., polio, & polio ), or just zoster ) is a glycol ether used as a in! An immune response is generated this page, enter your email address: we your... 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